Knock-Out Serum Replacement and Melatonin Effects on Germ Cell Differentiation in Murine Testicular Explant Cultures

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Enhancement in colonization of bovine spermatogonial stem cells following addition of knock-out serum replacement to culture medium

Enrichment of cell suspension with germ cells prior to injection into recipient seminiferous tubules is of importance in spermatogonial stem cells (SSCs) transplantation. Knock-out serum replacement (KSR) has been reported to enhance the proliferation of murine SSCs and human embryonic stem cells. The aim of the present study was to investigate the effect of KSR versus fetal bovine serum (FBS) ...

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ژورنال

عنوان ژورنال: Annals of Biomedical Engineering

سال: 2017

ISSN: 0090-6964,1573-9686

DOI: 10.1007/s10439-017-1847-z